2 juin 2022

Death of Marthe Gautier: co-signatory of the discovery of trisomy 21

Press release: The Jerome Lejeune Foundation salutes the memory of Marthe Gautier, collaborator of Jérôme Lejeune and co-signatory of the publication of the discovery of trisomy […]
9 mai 2022

Poster prize: Conference Jacques Monod

Genetics, Environment, Signaling, & Synaptic Plasticity in Developmental Brain Disorders: From Bench to Bedside 11-15 April 2022 Roscoff (France) Developmental Brain Disorders (DBDs) encompass a wide […]
21 mars 2022

Jérôme Lejeune Foundation -virtual- Postdoctoral Fellows meeting 2022

The Jerome Lejeune Foundation postdoctoral fellowships program started in 2017 in partnership with the Sisley-d’Ornano Foundation with the aim of supporting the career development of promising […]
22 février 2022

CBS, H2S and Down Syndrome: new results and new perspectives

The idea that a disequilibrium between homocysteine catabolism and the production the cysteine underlies some of the alterations observed in Down syndrome (DS) was suggested by […]
2 novembre 2021

Silencing the extra chromosome 21 in Down syndrome cells

Down syndrome (DS), caused by the complete or partial triplication of chromosome 21, presents a great challenge for research, medical care and development of therapies in […]
29 juin 2021

2021 Winners of the Jerome Lejeune Young Researcher Award

This year, the recipients of the Jerome Lejeune Young Researcher Award are two young scientists that are completing or have completed their PhD thesis on intellectual disabilities […]
23 juin 2021

Clinical trial: FRAXA-Funded Clinical Trial of PDE4D Inhibitor

Fragile X syndrome and phosphodiesterases Fragile X syndrome (FXS) is the most common form of inherited intellectual disability. It is a rare genetic neurodevelopmental disorder characterised […]
17 mai 2021

Down syndrome: a molecule that targets cognitive impairments enters the decisive phase of clinical trials

Significant headway has been made in recent years to understand the causes of intellectual disability in people with Down syndrome, but therapeutic research on this syndrome […]