Les projets subventionnés
par la Fondation Jérôme Lejeune
Session 2017b
15 projets
subventionnés par la Fondation Jérôme Lejeune
pour un montant de 510 513 €
Projets portant sur la Trisomie 21
Prof. Alberto Costa
Preclinical assessment of short-term sensory memory deficits in mouse models of Down syndrome: evaluation of a mismatch negativity paradigm
The Research Institute for Children’s Health (RICH)
Case Western Reserve School of Medicine
Cleveland (Ohio), USA
Dr. JM Delabar
Etude de l’efficacité d’un analogue de l’EGCG dans des modèles murins de trisomie 21
Institut du Cerveau et de la Moelle (Brain & Spine Institute)
CNRS UMR 7225, INSERM U1127, UPMC
France
Dr. Sandra Guidi
Prenatal treatment with a BDNF mimetic: a potential strategy for improving brain development in the Ts65Dn mouse model of Down syndrome
University of Bologna
Department of Biomedical and Neuromotor Sciences (DIBINEM)
Italy
Dr. Fernando Moldenhauer
Study of the renin-angiotensin-aldosterone system and its relation to the absence of atherosclerosis in adults with Down syndrome
Fundación de Investigació Biomédica Hospital de La Princesa
Unidad de Atención a Adultos con Sindrome de Down (MIH-UPDOWN)
Madrid, Spain
Prof. Lucio Nitsch
Therapeutic approach in Down syndrome by PGC-1alpha activation in differentiating neural cells
University of Naples Federico II
Laboratory of Cytogenetics and Cytogenomics
Department of Molecular Medicine and Medical Biotechnology
Italy
Prof. Alberto Costa
A drug repositioning approach for the discovery of DYRK1A regulators as a therapy for Down syndrome
Istituto di Ricovero e Cura a Carattere Scientifico « Giannina Gaslini »
Genova, Italy
Prof. Mary Rutherford
Serial MRI to assess early structural and functional brain development in Down syndrome for Developing Brain
Department of Perinatal Imaging and Health
Kings’ College London, United-Kingdom
Autres pathologies (syndromes tels que l’X fragile; Williams-Beuren; DiGeorge; Cri du chat…)
TEXT
Session 2018a
17 projets
subventionnés par la Fondation Jérôme Lejeune
pour un montant de 536 310 €
Projets portant sur la Trisomie 21
Text
Autres pathologies (syndromes tels que l’X fragile; Williams-Beuren; DiGeorge; Cri du chat…)
texte
Session 2018b
7 projets
subventionnés par la Fondation Jérôme Lejeune
pour un montant de 455 474 €
Projets portant sur la Trisomie 21
Texte
Apply for a Grant
The main target of the Jerome Lejeune Foundation, a non-profit foundation, is research into genetic diseases with intellectual disability.
If you are a researcher investigating on Down syndrome and other intellectual disability from genetic origin appearing in early childhood, the Scientific Advisory Board of the Jerome Lejeune Foundation invites you to submit your research project aiming at deciphering the pathophysiology of the cognitive deficits of patients, especially those (up to 50% of the total amount of the global grant) with Down syndrome (trisomy 21) and linked pathologies as well as knowledge of the chromosome 21.
The calls for proposals have
been changed!
The current Autumn call for proposals will be exclusively dedicated to Down syndrome research with Advanced and Pilot/exploratory grants.
Spring call for proposals (from mid-January to early March) will be dedicated to both Down syndrome and other rare intellectual disabilities from genetic origin such as Fragile X, cri du chat, Rett, Williams-Beuren, Prader-Willi, Angelman, Smith-Magenis and other syndromes, and will not exceed 50% of the total amount of the annual global grant. Autism not linked to above diseases is out of this call for grants.
Applications could cover fundamental, translational, epidemiological, clinical research, neurobiology, and pharmacology including animal pharmacology, genetic, genomic, iPSCs, and neuropsychology techniques or data analysis. Priority will be given to clinical research projects.
Two types of research projects may be submitted and will be separately evaluated
by the scientific board experts or external reviewers if needed for each call:
Advanced grants
Advanced grants will be dedicated to larger breakthrough projects with preliminary data. The maximum funding will be 80,000.00 € for a maximum of two years (i.e. 40,000.00 € per year for a maximum of two years). Ideally, two to four projects could be funded per call, but it could be more or les
Pilot or exploratory grants
Pilot or exploratory grants will be dedicated to initial early stage experiments built on preliminary data, or to ancillary projects to primary larger projects. The maximum funding will be 40,000.00 € for a maximum of two years (i.e. 20,000.00 € per year for a maximum of two years. The number of funded projects will depend of the annual global budget allocated by the Jerome Lejeune Foundation to the calls. Clinical projects could benefit from more funding.
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Through this call the Jerome Lejeune Foundation will also support the organization of conferences, workshops and courses. Such projects will also be reviewed by the Scientific Advisory Board.
Important
The funds provided by the Jerome Lejeune Foundation cannot in any way be used to purchase or make use of human embryonic or fetal tissues or another biological material obtained through direct abortions, IVF or human cloning or to create new human germinal cells. The Jerome Lejeune Foundation does not agree to be associated with such a work.
The researchers should mandatory follow their academic and national Good Laboratory Practices (GLP) (i.e. all measures that ensure, during the all research, quality, traceability and integrity of the data.).
Important
The funds provided by the Jerome Lejeune Foundation cannot in any way be used to purchase or make use of human embryonic or fetal tissues or another biological material obtained through direct abortions, IVF or human cloning or to create new human germinal cells. The Jerome Lejeune Foundation does not agree to be associated with such a work.
The researchers should mandatory follow their academic and national Good Laboratory Practices (GLP) (i.e. all measures that ensure, during the all research, quality, traceability and integrity of the data.).
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The funds provided by the Jerome Lejeune Foundation cannot in any way be used to purchase or make use of human embryonic or fetal tissues or another biological material obtained through direct abortions, IVF or human cloning or to create new human germinal cells. The Jerome Lejeune Foundation does not agree to be associated with such a work.
The researchers should mandatory follow their academic and national Good Laboratory Practices (GLP) (i.e. all measures that ensure, during the all research, quality, traceability and integrity of the data.).
Elementum, nec urna, ultrices id diam dolor.
Nunc cum diam et etiam. Senectus id malesuada vel ac eget scelerisque commodo eu morbi. Vel erat suspendisse eget suscipit ac venenatis, venenatis, imperdiet fusce. Et eget nibh vitae viverra lectus velit lectus proin sem. Viverra tempus vitae egestas sit velit faucibus. Commodo nulla neque malesuada orci malesuada.
Leo elit massa auctor integer sit bibendum. Viverra habitant a elit et consequat libero, non nulla ut. Tellus non velit morbi urna. Malesuada volutpat, sagittis, egestas orci, in metus, leo turpis. Justo, euismod purus ac, tellus. Erat dictum quis velit mauris rhoncus. Ut amet laoreet ullamcorper commodo mi placerat. Tellus amet, bibendum facilisi ultrices diam varius. Augue odio in convallis urna, varius egestas odio vitae. Facilisis sem orci urna, nibh vestibulum adipiscing neque amet mi. Eu aliquet porttitor sed odio pellentesque mauris, gravida viverra commodo. Neque arcu erat aenean adipiscing feugiat euismod vulputate molestie. Diam, semper eget tincidunt nulla vel neque, sit.
Cursus aliquam purus netus lacinia sed egestas eros tristique euismod. Platea at consequat elit lectus. Scelerisque sagittis massa odio leo consequat scelerisque. Hac lacus fames orci, blandit. Egestas sed pretium a, vulputate. Adipiscing senectus proin odio molestie orci. Elit in viverra sed scelerisque dictumst volutpat feugiat. Ultrices lectus at sed proin mauris velit amet aenean ac. Turpis tellus orci, facilisi purus scelerisque egestas massa arcu iaculis. Dictumst pharetra aliquam nibh maecenas pellentesque est.
The calls for proposals have been changed!
Leo elit massa auctor integer sit bibendum. Viverra habitant a elit et consequat libero, non nulla ut. Tellus non velit morbi urna. Malesuada volutpat, sagittis, egestas orci, in metus, leo turpis. Justo, euismod purus ac, tellus. Erat dictum quis velit mauris rhoncus. Ut amet laoreet ullamcorper commodo mi placerat. Tellus amet, bibendum facilisi ultrices diam varius. Augue odio in convallis urna, varius egestas odio vitae. Facilisis sem orci urna, nibh vestibulum adipiscing neque amet mi. Eu aliquet porttitor sed odio pellentesque mauris, gravida viverra commodo. Neque arcu erat aenean adipiscing feugiat euismod vulputate molestie. Diam, semper eget tincidunt nulla vel neque, sit.
Important
The funds provided by the Jerome Lejeune Foundation cannot in any way be used to purchase or make use of human embryonic or fetal tissues or another biological material obtained through direct abortions, IVF or human cloning or to create new human germinal cells. The Jerome Lejeune Foundation does not agree to be associated with such a work.
The researchers should mandatory follow their academic and national Good Laboratory Practices (GLP) (i.e. all measures that ensure, during the all research, quality, traceability and integrity of the data.).
Elementum, nec urna, ultrices id diam dolor.
Nunc cum diam et etiam. Senectus id malesuada vel ac eget scelerisque commodo eu morbi. Vel erat suspendisse eget suscipit ac venenatis, venenatis, imperdiet fusce. Et eget nibh vitae viverra lectus velit lectus proin sem. Viverra tempus vitae egestas sit velit faucibus. Commodo nulla neque malesuada orci malesuada.
- Leo elit massa auctor integer sit bibendum.
- Nunc cum diam et etiam. Senectus id malesuada vel ac eget scelerisque commodo eu morbi.
- Vel erat suspendisse eget suscipit ac venenatis, venenatis, imperdiet fusce.
- Et eget nibh vitae viverra lectus velit lectus proin sem.
- Viverra tempus vitae egestas sit velit faucibus.